23431c Praktikum

P Function and degeneration of the nervous system I

Peter Robin Hiesinger, Gerit Linneweber, Joachim Fuchs, Édouard Babo, Mathias Wernet

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Qualifikationsziele: Upon completion of this module, students will have acquired basic knowledge covering the most important methods in modern Neurobiology using genetic model organisms. Successful students will acquire skills covering several synergistic areas: (i) in modern neuroanatomy supported by molecular-genetic methods (including fluorescent and confocal microscopy), (ii) in the visualization and manipulation of neuronal activity in vivo, and (iii) in modern concepts and experimental approaches towards understanding neuronal degeneration on a mechanistic level. Students will be able to understand seminal publications in the field and to discuss them critically.

Inhalte: During the practical course, the students will learn about cutting-edge techniques for the investigation of key concepts in the synergistic field of neuronal function, maintenance and degeneration (from molecules to dynamic processes in the establishment of robust brain function). The lecture series will focus on genetic model organisms (mouse, zebrafisch, fly, worm), covering current topics relating to neuronal function, maintenance and degeneration, ranging from neuroanatomy to neurophysiology (including the visualization of intracellular transport, neuronal activity in the living animal, and manipulation of neuronal activity). In the seminar, specific papers will be discussed. Every student will present one research publication in form of an oral presentation (Referat).

Knowledge about modern, relevant research techniques will be acquired and applied. During the 4th week there will be no lectures or practical course, but one research paper as well as the results from the practical course will be orally presented on separate occasions. Schließen

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