216501a

Membrane Proteins: Classification, Structure and Function

Stefan Kubick

Information for students

Registration for the lecture by email to: stefan.kubick@fu-berlin.de) Then you will receive the access data. Classes 216501 a and b must be attended together. Their succesfull completion is obligatory for the application for the method module 216451 a, b! close

Comments

Content:
Biomembranes and synthesis of transmembrane proteins:

Molecular structure of membranes
Synthesis of biomembranes
Lipid rafts
Subcellular organization of the eukaryotic cell, cell metabolism and secretion
Protein synthesis

Receptors and signal transduction:

Cell surface receptors
Signal transduction pathways

Multigene families encoding membrane proteins:

G protein-coupled receptors (structure, signal transduction, agonists/antagonists)
Odorant receptors
Non-peptide receptors
Peptide receptors

Ion channels:

voltage-gated ion channels
ligand-gated ion channels
mechanosensitive ion channels

Methods in molecular biology and protein chemistry:

Production of membrane proteins
Cell-free protein synthesis (prokaryotic systems, eukaryotic systems, labeling)
Structural and functional analysis of membrane proteins

Dr. S. Kubick: stefan.kubick@fu-berlin.de
Fraunhofer Institut für Zelltherapie und Immunologie (IZI), Institutsteil Bioanalytik und Bioprozesse(IZI-BB) Potsdam-Golm, Am Mühlenberg 13, 14476 Potsdam close